Prof. Charles Mutai

    You are here:  
  1. Home
  2. Prof. Charles Mutai
Staff Profiles

Prof. Charles Mutai

mutai

Contact Details.
Department of Medical Laboratory Sciences
School of Public Health Biomedical Sciences and Technology (MMUST)
P.O. Box 190-50100
Kakamega, KENYA
Office no. ABA Block Room 401
Kakamega-Webuye Road.

Email: This email address is being protected from spambots. You need JavaScript enabled to view it. 

ResearcherID: AAP-1084-2021

ORCID: 0000-0002-9354-006X

Google Scholar:  00a43LMAAAAJ

Prof. Charles Mutai

Prof. Charles Mutai is Professor of Pharmacology and pharmacognosy at Masinde Muliro University of Science and Technology (MMUST), Department of Medical Laboratory Sciences. He joined the faculty at MMUST School of Health Sciences and Public Health, Biomedical Science and Technology in the year 2013. From January 1998 through 2012, Prof. Mutai was a Senior Researcher at the Kenya Medical Research Institute (KEMRI). He was also a World Health Organization (WHO) Postdoctoral Fellow at National Center for Drug Screening (NCDS) in Shanghai, China. Prof. Mutai was a member of the Tuberculosi Drug Development Group NCDS) in Shanghai, China. . His research has focused on sources of variability in drug response, which have emphasized modeling pharmacokinetics and pharmacodynamics relationships. His recent drug development efforts are directed towards coming up with new efficient drugs for TB and other chronic infectious diseases. Prof. Mutai has over 80 original publications in peer reviewed journals.

Some of his major publications:

  1. C Sagam, A Kivelenge, R Olayo, C Wanjala, C Mutai, B Wesonga, L Mutuli, J Situma. Effect of COVI-soup on cd4 cell count and haemoglobin among patients with diabetes type ii and hypertension in Kakamega County, Kenya: a randomized control trial. African Journal of Food,Publishe on 4th February 2023 in Agriculture, Nutrition and Development. DOI: https://doi.org/10.18697/ajfand.117.22910
  2. Sabella J. Kiprono, Gladys Mengich, Bartholomew N. Ondigo, Charles Mutai and SammyKimoloi. Therapeutic uses of stingless bee honey by traditional medicine practitioners in Baringo County, Kenya.Published on December 2022 in Journal of Pharmacognosy and Phytotherapy. DOI: https://doi.org/10.5897/JPP2022.0618
  3. Sabella J.Kiprono, Gladys Mengich, Jackline Kosgei, Charles Mutai, Sammy Kimoloi. Ethnomedicinal uses of stingless bee honey among native communities of Baringo County, Kenya.Scientific African. Available online 21 July 2022, e01297.In Press, Journal Pre-proof. https://doi.org/10.1016/j.sciaf.2022.e01297
  4. Wekesa J, Okoth J, Mutai C, Arudo J. The Contribution of Healthcare Workers’ Knowledge on Use of Integrated Palliative Care Approach in the Management of Chronic and Life Threatening Diseases at Kakamega County Referral Hospital, Kenya. World Scientific Research, 2018, vol. 5(1), pages 24-31. DOI: https://doi.org/10.20448/journal.510.2018.51.24.31.
  5. Lucia Keter, Richard Too, Nicholas Mwikwabe,Charles Mutai, Jennifer Orwa,Lizzy Mwamburi,Stanley Ndwigah,Christine Bii,Richard Korir. Risk of Fungi Associated with Aflatoxin and Fumonisin in Medicinal Herbal Products in the Kenyan Market. The Scientific World Journal.2017, (2017), 1-6.  DOI: https://doi.org/10.1155/2017/1892972.
  6. Georgine Kemboi, John Obiri, Charles Mutai. Knowledge, Awareness of Cervical Cancer among Women in Uasin Gishu County, Kenya. . International Journal of Sciences: Basic and Applied Research (IJSBAR), 2018, 41( 1), 167-180. ISSN 2307-4531.
  7. Georgine Jebet Kemboi, John F. Obiri, Charles C. Mutai. Knowledge, Attitudes and Socio-Cultural Practices that Influence the Control of Cervical Cancer among Women in Uasin Gishu County, Kenya. International Journal of Social Science and Humanities Research,2018,6(3),pg 553-562. ISSN 2348-3164.
  8. Lois M. Muiva-Mutisya, Yoseph Atilaw, Matthias Heydenreich, Andreas Koch, Hoseah M. Akala, Agnes C. Cheruiyot, Matthew L. Brown, Beatrice Irungu, Faith A. Okalebo, Solomon Derese, Charles Mutai, Abiy Yenesew. Antiplasmodial prenylated flavanonols from Tephrosia subtriflora. Natural Product Research, 2017, 1-8. DOI: https://doi.org/10.1080/14786419.2017.1353510.
  9. Muthaura CN, Keriko JM, Mutai C, Yenesew A, Heydenreich M, Atilaw Y, Gathirwa JW, Irungu BN, Derese S. "Antiplasmodial, Cytotoxicity and Phytochemical Constituents of Four Maytenus Species Used in Traditional Medicine in Kenya." The Natural Products Journal. 2017;7(2):144-152. DOI : https://doi.org/10.2174/2210315507666161206144050.
  10. Sally Jepkosgei Kiptoo, Charles Mutai and Mary Kipmerewo. Male partner involvement on maternal care services during perinatal period in Mumias East and West sub counties, Kakamega County, Kenya. Int. J. Adv. Res., 2016, 4(11), 1219-1232.DOI : http://dx.doi.org/10.21474/IJAR01/2206.
  11. Ameldah Barasa, Charles Mutai and Mary Kipmerewo. Effects of emergency obstetrics and neonatal care training on maternal and perinatal outcomes: Kakamega County, Kenya. Int. J. Adv. Res., 2016, 4(11), 1204-1218.DOI: https://doi.org/10.21474/IJAR01/2205.
  12. J.Mutuma, J.Wakhungu, C.Mutai. The socio economic effect of cancer on patients’ livelihoods in kenyan households. BIBECHANA 14 (2017) 30-36: RCOST p.38 (Online Publication: Dec., 2016) ISSN 2091-0762. DOI: https://doi.org/10.3126/bibechana.v14i0.15412.
  13. F.N. Kinoti, C Mutai, P Wanzala, S.M. Karanja Factors associated with infant feeding practices and nutritional status among children aged 6-24 months attending child welfare clinics in Kajiado Sub-County. East African Medical Journal, 2016, 93(8), 348-353.
  14. Lucia Keter, Richard Too, Charles Mutai, Nicholas Mwikwabe,Stanley Ndwigah, Jennifer Orwa, Elizabeth Mwamburi and Richard Korir. Bacteria Contaminants and their Antibiotic Sensitivity from Selected Herbal Medicinal Products from Eldoret and Mombasa, Kenya. American Medical Journal, 2016, 18-28. DOI: https://doi.org/10.3844/ajmsp.2016.18.28.
  15. Muthaura CN, Keriko JM, Mutai C, Yenesew A, Gathirwa JW, Irungu BN, Nyangacha R, Mungai GM, Derese S. Antiplasmodial potential of traditional phytotherapy of some remedies used in treatment of malaria in meru-tharaka nithi county of kenya. J Ethnopharmacol. 2015, 142-2. DOI: https://doi.org/10.1016/j.jep.2015.09.017
  16. Pascaline Jeruto, Ruth Nyangacha, Charles Mutai. In vitro and in vivo antiplasmodial activity extracts of selected Kenyan medicinal plants. Afr. J. Pharmacol. Ther. 2015, 4(4): 118-123.DOI: https://doi.org/10.5897/AJPP2013.3886.
  17. C N Muthaura , J M Keriko , C Mutai , A Yenesew , J W Gathirwa , B N Irungu , R Nyangacha , G M Mungai , S Derese .Antiplasmodial potential of traditional antimalarial phytotherapy remedies used by the Kwale community of the Kenyan Coast. J Ethnopharmacol. Epub 2015 May 20. https://doi.org/10.1016/j.jep.2015.05.024.
  18. Anuradha Kumar , Meng Zhang, Linyun Zhu, Reiling P Liao, Charles Mutai, Shittu Hafsat, David R Sherman, Ming-Wei Wang. High-throughput screening and sensitized bacteria identify an M. tuberculosis dihydrofolate reductase inhibitor with whole cell activity. PLoS One. 2012 Jun 29. DOI: https://doi.org/10.1371/journal.pone.0039961.
  19. Edward K Githinji 1, Lucy W Irungu, Willy K Tonui, Geoffrey M Rukunga, Charles Mutai, Charles N Muthaura, Reuben Lugalia, Geoffrey Gikandi, Caroline W Wainaina, Johnston M Ingonga, Antony Wanjoya. In vitro effects of Warburgia ugandensis, Psiadia punctulata and Chasmanthera dependens on Leishmania major promastigotes. Afr J Tradit Complement Altern Med 2010 Apr 3 https://doi.org/10.4314/ajtcam.v7i3.54791.
  20. Christine C Bii, Richard Korir, J Rugutt, Charles Mutai. The potential use of Prunus africana for the control, treatment and management of common fungal and bacterial infections. June 2010. Journal of Medicinal Plant Research.
  21. Laban N Ireri 1, Jedida Kongoro, Peter Ngure, Charles Mutai, Bernard Langat, Willy Tonui, Albert Kimutai, Obadiah Mucheru. The potential of the extracts of Tagetes minuta Linnaeus (Asteraceae), Acalypha fruticosa Forssk (Euphorbiaceae) and Tarchonanthus camphoratus L. (Compositae) against Phlebotomus duboscqi Neveu Lemaire (Diptera: Psychodidae), the vector for Leishmania major Yakimoff and Schokhor. J Vector Borne Dis . 2010 Sep;4 available online: https://pubmed.ncbi.nlm.nih.gov/20834087.
  22. Charles Mutai , Christine Bii, Constantinos Vagias, Dennis Abatis, Vassilios Roussis. Antimicrobial activity of Acacia mellifera extracts and lupane triterpenes. J Ethnopharmacol. Epub 2009 Feb 14. DOI: https://doi.org/10.1016/j.jep.2009.02.007.
  23. Lois M. Muiva, Abiy Yenesew, Solomon Derese, Matthias Heydenreich, Martin G. Peter, Hoseah M. Akala, Fredrick Eyase, Norman C. Waters, Charles Mutai, Joseph M. Keriko, Douglas Walsh. Antiplasmodial β-hydroxydihydrochalcone from seedpods of Tephrosia elata. Phytochemistry Letters. 24 August 2009. DOI: https://doi.org/10.1016/j.phytol.2009.01.002.

  24. Ngure, Peter Kamau; Tonui, Willy Kiprotich; Ingonga, Johnstone; Mutai, Charles; Kigondu, Elizabeth; Ng'ang'a, Zipporah; Rukunga, Geoffrey; Kimutai, Albert. In vitro antileishmanial activity of extracts of Warburgia ugandensis (Canellaceae), a Kenyan medicinal plant. Published in Journal of Medicinal Plants Research in 2009.

  25. Pascaline Jeruto 1, Catherine Lukhoba, George Ouma, Dennis Otieno, Charles Mutai. An ethnobotanical study of medicinal plants used by the Nandi people in Kenya. Published in Journal of Ethnopharmacology 5 March 2008 DOI: https://doi.org/10.1016/j.jep.2007.11.041.
  26. C Mutai, C Bii, G Rukunga, J Ondicho, P Mwitari, D Abatis, C Vagias, V Roussis, and J Kirui. Antimicrobial Activity of Pentacyclic Triterpenes Isolated from Acacia Mellifera. Afr J Tradit Complement Altern Med. Published online 2008 Oct 25. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816522/.
  27. Charles Mutai, Dennis Abatis, Constantinos Vagias, Dimitri Moreau, Christos Roussakis, Vassilios Roussis. Cytotoxic lupane-type triterpenoids from Acacia mellifera. Published in Phytochemistry Available online 24 March 2004. DOI: https://doi.org/10.1016/j.phytochem.2004.03.002.
  28. Pascaline Jeruto, Catherine Lukhoba, George Ouma, Dennis Otieno, Charles Mutai. Herbal treatments in Aldai and Kaptumo divisions in Nandi district, Rift valley province, Kenya. Afr J Tradit Complement Altern Med. 2007 Oct 27. Available on: https://pubmed.ncbi.nlm.nih.gov/20162062/.
  29. Charles Mutai , Dennis Abatis, Constantinos Vagias, Dimitri Moreau, Christos Roussakis, Vassilios Roussis. Lupane triterpenoids from Acacia mellifera with cytotoxic activity. Molecules. 2007 May 15. DOI: https://doi.org/10.3390/12051035.

View his full CV here

Live Search

Search