Contact details
Department of Biological Sciences
School of Natural and Applied Sciences (SONAS) MMUST
P.O. Box 190-50100
Kakamega, KENYA
Office no. SPD 310
Kakamega-Webuye Road
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
ORCID: https://orcid.org/0000-0001-8275-927X
Dr. Edna Ooko
Dr. Ooko holds a Doctorate degree in Pharmaceutical Biology specializing in the molecular, structural and genomic basis for drug resistance in cancer, malaria and bacterial diseases.She currently serves as a lecturer in the Department of Biological Sciences. Her areas of academic teaching and research are in Biochemistry and Plant Sciences in drug resistance in cancerous cells and antimicrobial resistance (AMR).
Some of her key published works include: -
- Ednah Ooko , Nadeen T. Ali and Thomas Efferth. Identification of Cuproptosis-Associated Prognostic Gene Expression Signatures from 20 Tumor Types. Published:Biolog on 3 October 2024. https://doi.org/10.3390/biology13100793 Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis.
- Christopher JL Murray, Kevin Shunji Ikuta, Samuel Aketch, Sarah Johnson, James Bukosia, Stephen Baker, Susan J Dunachie, Edna Ooko, Denis Garrett,……………………..……… et al. 2022 Jan 9 DOI: https://doi.org/10.1016/S0140-6736(21)02724-0. Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells.
- Ooko E, Saeed ME, Kadioglu O, Sarvi S, Colak M, Elmasaoudi K, Janah R, Greten HJ, Efferth T.Phytomedicine. 2015 Oct 15;22(11):1045-54. doi: 10.1016/j.phymed.2015.08.002. Epub 2015 Aug 18. PMID: 26407947 Biopiracy of natural products and good bioprospecting practice.
- Efferth T, Banerjee M, Paul NW, Abdelfatah S, Arend J, Elhassan G, Hamdoun S, Hamm R, Hong C, Kadioglu O, Naß J, Ochwangi D, Ooko E, Ozenver N, Saeed ME, Schneider M, Seo EJ, Wu CF, Yan G, Zeino M, Zhao Q, Abu-Darwish MS, Andersch K, Alexie G, Bessarab D, Bhakta-Guha D, Bolzani V, Dapat E, Donenko FV, Efferth M, Greten HJ, Gunatilaka L, Hussein AA, Karadeniz A, Khalid HE, Kuete V, Lee IS, Liu L, Midiwo J, Mora R, Nakagawa H, Ngassapa O, Noysang C, Omosa LK, Roland FH, Shahat AA, Saab A, Saeed EM, Shan L, Titinchi SJ.Phytomedicine. 2016 Feb 15;23(2):166-73. doi: 10.1016/j.phymed.2015.12.006. Epub 2016 Jan 9. PMID: 26926178 Review. Biopiracy versus One-World Medicine-From colonial relicts to global collaborative concepts.
- Efferth T, Banerjee M, Abu-Darwish MS, Abdelfatah S, Böckers M, Bhakta-Guha D, Bolzani V, Daak S, Demirezer ÖL, Dawood M, Efferth M, El-Seedi HR, Fischer N, Greten HJ, Hamdoun S, Hong C, Horneber M, Kadioglu O, Khalid HE, Khalid SA, Kuete V, Mahmoud N, Marin J, Mbaveng A, Midiwo J, Nakagawa H, Naß J, Ngassapa O, Ochwang'i D, Omosa LK, Ooko EA, Özenver N, Poornima P, Romero MR, Saeed MEM, Salgueiro L, Seo EJ, Yan G, Yasin Z, Saeed EM, Paul NW.Phytomedicine. 2019 Feb; 53:319-331. doi: 10.1016/j.phymed.2018.06.007. Epub 2018 Jun 11. PMID: 30190231 Review. Collateral Sensitivity of Parthenolide via NF-κB and HIF-α Inhibition and Epigenetic Changes in Drug-Resistant Cancer Cell Lines.
- Dawood M, Ooko E, Efferth T.Front Pharmacol. 2019 May 21;10:542. doi: 10.3389/fphar.2019.00542. eCollection 2019.PMID: 31164821 Free PMC article. In Silico and In Vitro Screening of 50 Curcumin Compounds as EGFR and NF-κB Inhibitors.
- Saeed MEM, Yücer R, Dawood M, Hegazy MF, Drif A, Ooko E, Kadioglu O, Seo EJ, Kamounah FS, Titinchi SJ, Bachmeier B, Efferth T.Int J Mol Sci. 2022 Apr 2;23(7):3966. doi: 10.3390/ijms23073966.PMID: 35409325 Free PMC article. Pharmacogenomic Characterization and Isobologram Analysis of the Combination of Ascorbic Acid and Curcumin-Two Main Metabolites of Curcuma longa-in Cancer Cells.
- Ooko E, Kadioglu O, Greten HJ, Efferth T.Front Pharmacol. 2017 Feb 2;8:38. doi: 10.3389/fphar.2017.00038. eCollection 2017.PMID: 28210221 Free PMC article. Modulation of P-glycoprotein activity by novel synthetic curcumin derivatives in sensitive and multidrug-resistant T-cell acute lymphoblastic leukemia cell lines.
- Ooko E, Alsalim T, Saeed B, Saeed MEM, Kadioglu O, Abbo HS, Titinchi SJJ, Efferth T.Toxicol Appl Pharmacol. 2016 Aug 15;305:216-233. doi: 10.1016/j.taap.2016.06.002. Epub 2016 Jun 16.PMID: 27318188
