Dr Sammy Kimoloi

Contact details

kimoloiDepartment of Internal Medicine

School of Medicine (MMUST)

P.O. Box 190-50100

Kakamega, KENYA

Office no. MED Block 2nd floor Room

Kakamega-Webuye Road

Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

ORCID: https://orcid.org/0000-0003-3364-4980

Research gate https://www.researchgate.net/profile/Sammy 

Google Scholar: kwXl0OoAAAAJ

Dr Sammy Kimoloi

Dr Sammy Kimoloi holds doctorate degree in Molecular Medicine from University of Cologne Germany, MSc Clinical Pharmacology, Glasgow University UK, and BSc Biomedical sciences (Pharmacology and Physiology), Maseno, Kenya. His areas of academic and research interest are in the fields of mitochondrial medicine, molecular epidemiology and mechanisms of drug resistance (C.difficille and C auris) as well as novel drug discovery and development. His major scholarly contribution so far is elucidation of the role of mtDNA deletions in the pathogenesis of Sarcopenia and mitochondrial myopathy.

Some of his key published works include: -

  1. Johnson Masese, Gilbert Kipkoech, Sammy Kimoloi, Peter Mwitari, Gordon Nguka, Charles Mutai. Protective effect of Spirulina platensis extract on aflatoxin B1 immunotoxicities in mice. J Phytopharmacol 2023; 12(1):27-31. https://phytopharmajournal.com/assets/pdf_files/Vol12_Issue1_04.pdf DOI: https://doi:10.31254/phyto.2023.12104
  1. Sabella J. Kiprono, Gladys Mengich, Bathlomew N. Ondigo, Charles Mutai, Sammy Kimoloi (2022) Therapeutic uses of stingless bee honey by traditional medicine practitioners in Baringo County, Kenya, J. Pharmacognosy Phytother Vol. 14(3), pp. 27-36, October-December 2022. https://doi.org/10.5897/JPP2022.0618
  1. Sabella J. Kiprono, Gladys Mengich, Jackline Kosgei, Charles Mutai, Sammy Kimoloi, (2022) Ethnomedicinal uses of stingless bee honey among native communities of Baringo County, Kenya, Scientific African, Volume 17,e01297,ISSN 2468-2276, https://doi.org/10.1016/j.sciaf.2022.e01297.
  2. Kimoloi, S., Sen, A., Guenther, S., Braun, T., Brügmann, T., Sasse, P., Wiesner, R. J., Pla-Martín, D.,and Baris, O. R. (2022) Combined fibre atrophy and decreased muscle regeneration capacity driven by mitochondrial DNA alterations underlie the development of sarcopenia, Journal of Cachexia, Sarcopenia and Muscle: https://doi.org/10.1002/jcsm.13026
  1. Kimoloi, S., D. Pla-Martin, R. R. Oexner, O. R. Baris and R. J. Wiesner (2021). "Author Response: K320E-Twinkleskm Mice Are Genetically Heterogeneous for Secondary mtDNA Deletions Impairing Comparison With Controls." Invest Ophthalmol Vis Sci 62(1): 13. doi: 1167/iovs.62.1.13
  1. Basu, S., X. Xie, J. P. Uhler, C. Hedberg-Oldfors, D. Milenkovic, O. R. Baris, Kimoloi, S. Matic, J. B. Stewart, N. G. Larsson, R. J. Wiesner, A. Oldfors, C. M. Gustafsson, M. Falkenberg and E. Larsson (2020). "Accurate mapping of mitochondrial DNA deletions and duplications using deep sequencing." PLoS Genet 16(12): e1009242. https://doi.org/10.1371/journal.pgen.1009242
  1. Oexner, R. R., D. Pla-Martin, T. Pass, M. H. J. Wiesen, P. Zentis, A. Schauss, O. R. Baris, Kimoloi and R. J. Wiesner (2020). "Extraocular Muscle Reveals Selective Vulnerability of Type IIB Fibers to Respiratory Chain Defects Induced by Mitochondrial DNA Alterations." Invest Ophthalmol Vis Sci 61(12): 14. https://doi.org/10.1167/iovs.61.12.14
  1. Imhof, T., K. Rosenblatt, G. Pryymachuk, D. Weiland, N. Noetzel, J. Deschner, O. R. Baris, Kimoloi, M. Koch, R. J. Wiesner and Y. Korkmaz (2020). "Epithelial loss of mitochondrial oxidative phosphorylation leads to disturbed enamel and impaired dentin matrix formation in postnatal developed mouse incisor." Sci Rep 10(1): 22037. https://doi.org/10.1038/s41598-020-77954-7
  1. Ricke, K. M., T. Pass, Kimoloi, K. Fahrmann, C. Jungst, A. Schauss, O. R. Baris, M. Aradjanski, A. Trifunovic, T. M. Eriksson Faelker, M. Bergami and R. J. Wiesner (2020). "Mitochondrial Dysfunction Combined with High Calcium Load Leads to Impaired Antioxidant Defense Underlying the Selective Loss of Nigral Dopaminergic Neurons." J Neurosci 40(9): 1975-1986. https://doi.org/10.1523/JNEUROSCI.1345-19.2019
  1. Gnaiger E, Aasander Frostner E, Abdul Karim N, Abdel-Rahman EA, Abumrad NA, Acuna-Castroviejo D, Adiele RC, et al(2019) "Mitochondrial respiratory states and rates."  Bioenerg Commun 2020.1. doi:10.26124/bec:2020-0001.v1
  1. Kimoloi, S. (2018). "Modulation of the de novo purine nucleotide pathway as a therapeutic strategy in mitochondrial myopathy." Pharmacol Res 138: 37-42. https://doi.org/10.1016/j.phrs.2018.09.027
  1. Magomere, E. O., D. D. Nyangahu, Kimoloi, B. A. Webala and B. N. Ondigo (2019). "Performance characteristics of a modified HIV-1 drug resistance genotyping method for use in resource-limited settings." F1000Res 8: 1518. https://doi.org/10.12688/f1000research.20083.1
  2. Kimoloi, S. and K. Rashid (2015). "Potential role of Plasmodium falciparum-derived ammonia in the pathogenesis of cerebral malaria." Front Neurosci 9: 234. https://doi.org/10.3389/fnins.2015.00234
  1. Kimoloi S., Nicky O., Ondigo BM., Langat BK (2013). Choice and sources of antimalarial drugs used for self-medication in Kisumu, Western Kenya. Afr J Pharm Ther 2: 124-129.
  1. Langat BK., Kiboi D., Irungu B., Kimoloi S., Nyambati V., and Rukunga R. (2012.) Lumefantrine-resistant and Piperaquine-resistant Plasmodium berghei show cross-resistance to Primaquine but not to Atovaquone Afr J Pharm Ther 1: 35-40.

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